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Amoxicillin and clavulanate combination is used to treat bacterial infections in many different parts of the body (eg, ear, lungs, sinus, skin, urinary tract). 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It's also used in post-operative infections and can be used to treat bacterial meningitis. The combination works by inhibiting bacterial cell wall synthesis (cefoperazone) and preventing bacterial resistance to cefoperazone (tazobactam). 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