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Ketoconazole and tolnaftate is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection. Clioquinol belongs to a category of drugs called hydroxyquinoline antifungal agents. It acts by interacting with DNA synthesis thus killing the fungi that are responsible for causing the infection. Neomycin is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Clobetasol is a steroid. 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