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It works by preventing bacteria from forming cell walls, thus inhibiting their growth and spread. This specific combination is often used when the infection is suspected to be resistant to other antibiotics. 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It's effective against both Gram-positive and Gram-negative bacteria, and is particularly useful for infections like pneumonia, urinary tract infections, skin and skin structure infections, and complicated intra-abdominal infections (when used with metronidazole). It's also used to treat febrile neutropenia, a condition where patients have a fever and low white blood cell count, increasing their risk of infection. 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