Doxirut-50: Cefpodoxime 50mg Dry Syrup for Pediatric Infections
Product Overview
Doxirut-50 is a premium pediatric antibiotic formulation containing Cefpodoxime Proxetil 50mg in dry syrup form, manufactured by Medroots Biopharma India Pvt Ltd. This third-generation cephalosporin antibiotic is specifically designed for treating bacterial infections in children across India.
Key Product Information
Brand Name: Doxirut-50
Generic Name: Cefpodoxime Proxetil
Strength: 50mg per 5ml (when reconstituted)
Formulation: Dry Syrup for Oral Suspension
Manufacturer: Medroots Biopharma India Pvt Ltd
Availability: Pan India Distribution
Category: Prescription Antibiotic for Pediatric Use
What is Cefpodoxime 50mg Dry Syrup?
Cefpodoxime is a broad-spectrum, third-generation cephalosporin antibiotic that effectively treats various bacterial infections in children. Doxirut-50 dry syrup provides a convenient, palatable formulation that ensures accurate dosing and improved compliance in pediatric patients.
Pediatric Uses and Indications
Doxirut-50 is prescribed for treating the following bacterial infections in children:
Respiratory Tract Infections
Acute otitis media (middle ear infections)
Pharyngitis and tonsillitis
Community-acquired pneumonia
Acute bronchitis
Sinusitis
Skin and Soft Tissue Infections
Cellulitis
Impetigo
Skin structure infections
Wound infections
Urinary Tract Infections
Uncomplicated urinary tract infections
Cystitis
Pyelonephritis (when appropriate)
Other Infections
Gonorrhea (in adolescents)
Cervicitis and urethritis
Dosage and Administration
Recommended Pediatric Dosing
Age 2 months to 12 years: 10mg/kg/day divided into two doses
Maximum daily dose: 400mg
Duration: Typically 5-10 days as prescribed by physician
Administration: With or without food
Reconstitution Instructions
Add specified amount of boiled and cooled water
Shake well until completely dissolved
Store reconstituted suspension in refrigerator
Use within 14 days of reconstitution
Shake well before each use
Key Benefits of Doxirut-50
Clinical Advantages
Broad-spectrum coverage against gram-positive and gram-negative bacteria
High bioavailability ensuring effective therapeutic levels
Twice-daily dosing improving medication compliance
Pleasant taste for better pediatric acceptance
Stable formulation with extended shelf life
Safety Profile
Well-tolerated in pediatric populations
Lower incidence of gastrointestinal side effects
Minimal drug interactions
Safe for use in children with penicillin allergies (with proper medical supervision)
Mechanism of Action
Cefpodoxime works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). This bactericidal action effectively eliminates susceptible bacteria, making it highly effective against common pediatric pathogens including:
Streptococcus pneumoniae
Haemophilus influenzae
Moraxella catarrhalis
Staphylococcus aureus
Escherichia coli
Klebsiella pneumoniae
Why Choose Doxirut-50?
Quality Assurance
Manufactured by Medroots Biopharma India Pvt Ltd
Strict quality control standards
WHO-GMP certified manufacturing facility
Consistent potency and purity
Healthcare Provider Benefits
Proven efficacy in pediatric infections
Comprehensive bacterial coverage
Convenient twice-daily dosing
Excellent safety profile
Cost-effective treatment option
Parent and Child Benefits
Pleasant-tasting formulation
Easy-to-administer liquid form
Rapid symptom relief
Shorter treatment duration
Minimal side effects
Storage and Handling
Before reconstitution: Store below 25°C in dry place
After reconstitution: Refrigerate at 2-8°C
Shelf life: 24 months from manufacturing date
Reconstituted stability: 14 days when refrigerated
Keep out of reach of children
Important Safety Information
Contraindications
Hypersensitivity to cefpodoxime or other cephalosporins
Severe renal impairment
History of cephalosporin-associated colitis
Precautions
Use with caution in penicillin-allergic patients
Monitor renal function in prolonged therapy
Complete full course as prescribed
Inform healthcare provider of all concurrent medications
Common Side Effects
Mild gastrointestinal upset
Diarrhea
Nausea
Headache
Skin rash (rare)
Prescription Information
Doxirut-50 is a prescription-only medicine that should be used under medical supervision. Healthcare providers should:
Confirm bacterial infection before prescribing
Consider local resistance patterns
Ensure appropriate dosing based on child's weight and age
Monitor treatment response
Educate parents on proper administration
Availability Across India
Doxirut-50 is available through authorized pharmaceutical distributors and pharmacies across all states and union territories of India. The product maintains consistent quality and availability through Medroots Biopharma's extensive distribution network.
Frequently Asked Questions
Can Doxirut-50 be given with food?
Yes, Cefpodoxime can be administered with or without food. Taking with food may help reduce stomach upset.
What if a dose is missed?
Give the missed dose as soon as remembered, unless it's almost time for the next dose. Never double the dose.
How quickly does Doxirut-50 work?
Most children show improvement within 48-72 hours. Complete the full course even if symptoms improve.
Is Doxirut-50 safe for infants?
Consult your pediatrician for appropriate use in children under 2 months of age.
Contact Information
For medical inquiries and product information:
Medroots Biopharma India Pvt Ltd
Available through authorized medical representatives
Pharmacovigilance reporting available
Healthcare provider support services
contact-no-6284828066
